Nitric Oxide in Single-Breath Exhalation in Humans.
نویسندگان
چکیده
منابع مشابه
Nasal contribution to exhaled nitric oxide during exhalation against resistance or during breath holding.
BACKGROUND The concentration of nitric oxide (NO) is increased in the exhaled air of patients with inflammation of the airways, suggesting that this may be a useful measurement to monitor inflammation in diseases such as asthma. However, there have been concerns that exhaled NO may be contaminated by the high concentrations of NO derived from the upper airways, and that this may account for dif...
متن کاملExhaled single-breath nitric oxide measurements are reproducible, repeatable and reflect levels of nitric oxide found in the lower airways.
Measurement of exhaled nitric oxide (NO) may allow noninvasive assessment of inflammatory disease in the lung. We determined immediate and day-to-day reproducibility of single-breath NO measurements at different points on the exhaled test, and whether levels recorded reflect levels of NO in the lower airways. Using a rapid chemiluminescence analyser, 55 healthy control subjects performed three ...
متن کاملNitric oxide-endothelin-1 interaction in humans.
Healthy men received NG-monomethyl-L-arginine (L-NMMA) intravenously to study cardiovascular and metabolic effects of nitric oxide synthase blockade and whether this alters the response to endothelin-1 (ET-1) infusion. Controls only received ET-1. L-NMMA effects were that heart rate (17%) cardiac output (17%), and splanchnic and renal blood flow (both 33%) fell promptly (all P < 0.01). Mean art...
متن کاملATS workshop proceedings: exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate.
The field of noninvasive assessment of airway inflammation has developed rapidly since the discoveries in the late 1980s that nitric oxide (NO) is a central biological mediator and, in 1991, that exhaled breath contained NO (1). Accompanying this was the realization that asthma is an inflammatory airway syndrome, best treated by antiinflammatory agents. Subsequently, exhaled NO was found to be ...
متن کاملNitric oxide measured with single-breath and tidal-breathing methods in asthma and COPD.
Nitric oxide (NO) can be measured in exhaled air with the single-breath (SB) and tidal-breathing (TB) methods. To allow comparison between different laboratories, a European Respiratory Society task force recently reported guidelines for standardization of both methods. To facilitate comparison between laboratories further, this study investigated whether there is a difference between NO values...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1997
ISSN: 0021-521X
DOI: 10.2170/jjphysiol.47.335